Observe Intently (one)pentobarbital will lessen the level or impact of buprenorphine subdermal implant by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Keep track of Closely. Observe clients already on buprenorphine subdermal implant who have to have freshly-initiated procedure with CYP3A4 inducer for indications and sympt
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